I have been busy over the past couple of weeks having a final catch-up with portfolio companies before Christmas and there is a positive overarching theme.  All CEOs who have recently been to trade shows have reported a dramatic change in sentiment within their markets.

Harry Hatzakis at Biotronics 3D could barely contain his excitement today when talking about people queuing at the stand at RSNA (Radiologist Conference) in Chicago.  He reported interest from multinationals as well as smaller companies. 

 Eddy Littler (CEO of Domainex) returned in November from BIO-Europe saying that it had been the best week since he joined the company in January 2008.  That sentiment was echoed by Keith Powell (CEO of Polytherics).  Both were on the receiving end of interest from both large pharma and smaller biotech seeking collaboration. 

If this continues, 2010 will be a good year.